9.09.2010

OB/Gyn clinical notes

Pap smear starts @ 21 or new onset intercourse
Abnormal pap, LEEP- surgery for dysplastic cervix, increased risk for prematurity on successive pregnancy, cervical shortening.

gonorrhea, chlamydia - test with urine

>30 years old? Pap + HPV is very sensitive (can rule you out), if -/- don't repeat for 3 yrs

vaginal pH - low, blood, semen, rupture of membrane increases pH


three major infections in GU
yeast - cottage cheese, no change in pH
trichomoniasis -erythema, greenish yellow frothy, increases pH
bacterial vaginosis - grey spilled milk, increases pH
-whiff test - KOH tx and smells bad, or have sex without condom and alkaline sperm create bad smell, clue cells

bacterial vaginosis, trichomonas treated with metronidazole

"chandelier sign" - moving the cervix causes great pain, sing of peritoneal tenderness

acute cystitis - UTI
chronic cystitis (interstitial) disease of lining of bladder, chronic UTI w/neg culture, avoid acidic, citric, spice, tylenol

fetal heart rate monitoring
keep track of
1. rate
2. variability
3. accels/decels
4. uterine contractions

reactive heart rate should accelerate to
<32>10 bpm for 10 seconds x2 within 20 minutes
>32 weeks gestation? fhr accelerate>15 bpm for 10 seconds x2 within 20 minutes
late decelerations happen after uterine contraction, very bad, sign of fetal hypoxia, possible uteroplacental insufficiency

4 questions to ask every antepartum mother every morning?
1. any contractions/cramping?
2. any vaginal bleeding?
3. any fluid leakage? water break?
4. any fetal movments?

actinomyces is associated with IUD's, treatment is penicillin


Endometrial Cancer
US 40,000 cases annually, 4-5,000 deaths
typical clinical presentation is post-menopausal bleeding

risk factors
obesity - adipose contains aromatase (converts estrogen)
nulliparity
smoking is protective because nicotine by products induce clearance of estrogen, ^ binding
globulin
tamoxifen
HNPCC - hereditary nonpolyposis colorectal cancer - in young presentations

atypical hyperplasia - 30% go on to develop cancer

Diagnostics
Ultrasound - $1,800 good negative predictive value
Biopsy - $100's, 80-90% sens/spec
D&C better but con is surgery

Woman >35yrs w/menorrhagia? Sample.

Prognosis - Grade very important, higher grade lower prognosis, more than stage

Stage
Ia <1/2cm>
Ib >1/2cm invasion into myometrium
II stromal invasion
IIIa - serosa/tube/adnexal
b - vagina
c - nodes (pelvic, periaortic)
IV a bladder/rectal mucosa
b Distant

Treatment
surgery (uterus, nodes, bilateral salpingoopherectomy)
low risk? no further tx
intermediate risk? radiation (pelvic vs intracavitary brachytherapy)
high risk? chemo + radiation


Anesthesia in Labor-

somatic vs visceral pain

visceral pain - hard to localize, first stage of labor, well treated w/opioids
somatic pain - stage two in labor,

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