order MR if question about age of hemorrhage
(classically in child abuse cases)
hemorrhage on CT
white 2/2 Hgb/protein concentratino ~56 HU, anemic patient may appear isodense
hyper acute blood 0-72 hyperdense
Early subacute 3 days 1 week still hyperdense
Late subacute hypodense 1 week to months
MRI
2 factors affect MR: oxygenation state of hemoglobin, lysi of initially intact RBC
hyperacute 3-6hours - contains oxyhemoglobin (diamagnetic) - will not see it on GRE/SWI
acute 8-72 hrs - ^ deoxyhemoglobin (paramagnetic) will see on SWI/GRE
chronic hemorrhage - months to years, iron atoms deposited and cannot exit
hyper acute
oxy - isointense T1, bright on T2
acute 1-3 days
deoxy - iso on T1 dark on T2
subacute )3-7days)
bright on TI, dardk on T2
late 7-14 days bright bright - extracellular methemoglobin
chronic >14 days - dark dark T1T2
intracranial vasculature
digital subtractio angiography - gold standard, catheter angiography
do each vessel individually
bolus injection 100ml at 4-6ml/sec
large bore 18guage antecubital to get good cta
MRA/V
TOF - no contrast - moving spins experience different excitations (flow related), slow flow may appear as if vessel is occluded - can see >1.5mm on 1.5T
2D limitations - need adequate flow, aneurysms poorly visualized, underestimated because of slow moving spins
Phase contrast -
TRICKS - time resolved iagin of contrast kinetics: needs contast -time resolved imaging of contrast
giant aneurysm >2.5cm presents w/mass effect
http://www.youtube.com/watch?v=_OJ5qnErsTc&NR=1
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