renal clinical notes

renal notes

immune complex GN

post strep/infectious

SLE (full house)

MPGN (HCV)

IgA nephropathy

anti-GBM (very fast onset)

affects renal, lung or both (goodpastures)

pauci immune

vasculitis

sore throat + GN same day = IgA (no time lag)

sore throat + GN later = post strep

microscopic polyangiitis - lungs are whited out

wegener's - lung nodules

systemic disease (nodules, purpura, ulcers, sinusitis)

Pulmonary and Renal

lung vasculitis - lupus, henoch schonlein purpura, wegeners, microscopic polyangiitis

pneumonia/sepsis major cause of ATN

ANCA is to RPGN as antiDNA is to lupus

tx of vasculitis - cytoxan + steroids + plasmapharesis

IgA nephropathy -renal

HSP - systemic

IgA nephropathy treatment - ACEi

if > 1gm protein in urine 50% loss of renal function in ten years

Lupus - endocaopillary proliferation

Serum complement is low with

MPGN

Lupus

Post infectious

Complement is normal with

IgA neph

anti-GBM

ANCA-RPGN/Wegeners

Anemia + decrease plts? could be thrombotic microangiopathy

when doing a kidney biopsy a drop in Hgb of 1.0g/dL is no problem